Abstract Bacteria have unique abilities. The interaction with microbes in the human body forms a "united front" in the form of biofilm, actively evading the response of the human immune system and improving the antibiotic resistance of bacteria. The direct consequences, based on bacteria...
Bacteria have unique abilities, and the interaction of microorganisms in the human body forms a "united front" in the form of biofilm, actively evading the response of the human immune system and improving the antibiotic resistance of bacteria. The direct consequence of this is that bacterial biofilm-based infections are generally difficult to eradicate. More serious is the long-term inadvertent use of antibiotics, resulting in emerging bacterial microbial antibiotic resistance, further strengthening the threat of bacterial biofilm infection. With the continuous advancement of nanotechnology, nanotechnology is increasingly used in modern medicine, such as nano imaging probes and nano-targeted drug carriers. The EU's Seventh Research and Development Framework Program (FP7) provides a full funding of 200,000 Euros, a European PHOTORELEASE R&D team consisting of three EU member states (General Coordination), UK and Spanish nanomedical researchers. Actively utilizing the unique inertness, biocompatibility of nanodiamond particles and the ability to easily realize functional engineering design according to demand, the non-Biocidal engineering design actively responds to bacterial microbial biofilm antibiotic resistance.
The research of the R&D team has made positive progress. Make full use of the function of anti-Adhesive Molecules to prevent the interaction of bacterial microbes to form a biofilm symbiotic relationship, so as to achieve the healing effect of biofilm infection. The technology can also be applied to the surface of various medical devices to remove bacterial microorganisms.
The R&D team has successfully developed sugar coated nanodiamond particle inhibitors to prevent the formation of E. coli based biofilms. Through trial and error, the function of nanodiamond particles is continuously revised and optimized to help improve the actual effect of biofilm resistance.
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