Xinhua News Agency, Tokyo, August 29 (Reporter Qian Yu) Japanese researchers found in animal experiments that a compound can inhibit the synthesis of intracellular fat. This result is helpful for the development of drugs for the treatment of metabolic syndrome.
Researchers from institutions such as Kyoto University and the University of Tokyo published a paper in the online edition of the new issue of Chemistry and Biology. They analyzed the characteristics of 30,000 compounds and found that there is a substance that can hinder the synthesis of intracellular fat. . The researchers named the compound "Fatstatin."
The researchers first cultivated a group of lab rats that had a strong appetite to keep eating, and then injected a part of the mice with this compound. One month later, mice that had not received injections of compounds increased their body weight from 25 to 36 grams, and suffered from high blood sugar and fatty liver. The mice injected with the compound had little change in body weight even if they continued to eat the same compound. Also normal.
The analysis found that this compound combined with proteins necessary for the synthesis of fat in the cells of rats' livers and other organs inhibited the synthesis of fat.